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Structure paper

TitleTargeting an essential step in the biosynthetic pathway of uridine diphosphate glucose in Aspergillus fumigatus
Journal, issue, pagesTo Be Published
Publish dateJul 14, 2021 (structure data deposition date)
AuthorsYan, K. / Stanley, M. / Kowalski, B. / Raimi, O.G. / Ferenbach, A.T. / Wei, P.Z. / Yuan, H. / Fang, W. / van Aalten, D.M.F.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.11 - 2.48 Å
Structure data

PDB-7p5o:
Crystal structure of Aspergillus fumigatus phosphoglucomutase in complex with the reaction intermediate
Method: X-RAY DIFFRACTION / Resolution: 2.48 Å

PDB-7piz:
The structure of phosphoglucomutase from Candida albicans
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

PDB-7pjc:
The structure of Candida albicans phosphoglucomutase with isothiazolone modification on Cys359
Method: X-RAY DIFFRACTION / Resolution: 2.11 Å

Chemicals

ChemComp-G16:
1,6-di-O-phosphono-alpha-D-glucopyranose

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

ChemComp-A4W:
~{N}-(3-chloranyl-2-fluoranyl-phenyl)-3-sulfanyl-propanamide

ChemComp-GOL:
GLYCEROL

Source
  • aspergillus fumigatus (mold)
  • candida albicans p75010 (yeast)
  • candida albicans sc5314 (yeast)
KeywordsISOMERASE / phosphoglucomutase; sugar nucleotide; glucan; UDP-Glc / phosphoglucomutase / candida / fungi

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