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-Structure paper
Title | TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation. |
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Journal, issue, pages | Mol. Cell, Vol. 81, Page 2705-, Year 2021 |
Publish date | Aug 10, 2020 (structure data deposition date) |
Authors | Fitzian, K. / Bruckner, A. / Brohee, L. / Zech, R. / Antoni, C. / Kiontke, S. / Gasper, R. / Linard Matos, A.L. / Beel, S. / Wilhelm, S. ...Fitzian, K. / Bruckner, A. / Brohee, L. / Zech, R. / Antoni, C. / Kiontke, S. / Gasper, R. / Linard Matos, A.L. / Beel, S. / Wilhelm, S. / Gerke, V. / Ungermann, C. / Nellist, M. / Raunser, S. / Demetriades, C. / Oeckinghaus, A. / Kummel, D. |
External links | Mol. Cell / PubMed:33974911 |
Methods | X-ray diffraction |
Resolution | 2.32 - 4.3 Å |
Structure data | PDB-7a0m: PDB-7a0n: |
Chemicals | ChemComp-SO4: ChemComp-HOH: |
Source |
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Keywords | SIGNALING PROTEIN / TSC / GAP / GTPase signaling / TSC1 / GTPase |