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TitleThe Stringent Response Inhibits 70S Ribosome Formation in Staphylococcus aureus by Impeding GTPase-Ribosome Interactions.
Journal, issue, pagesMbio, Vol. 12, Page e0267921-e0267921, Year 2021
Publish dateJun 23, 2020 (structure data deposition date)
AuthorsBennison, D.J. / Nakamoto, J.A. / Craggs, T.D. / Milon, P. / Rafferty, J.B. / Corrigan, R.M.
External linksMbio / PubMed:34749534
MethodsX-ray diffraction
Resolution1.94 - 2.15 Å
Structure data

PDB-6zhl:
Crystal Structure of Staphylococcus aureus RsgA bound to ppGpp.
Method: X-RAY DIFFRACTION / Resolution: 1.94 Å

PDB-6zhm:
Crystal Structure of Staphylococcus aureus RsgA bound to GDP.
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

PDB-6zjo:
Crystal Structure of Staphylococcus aureus RsgA.
Method: X-RAY DIFFRACTION / Resolution: 2.01 Å

Chemicals

ChemComp-G4P:
GUANOSINE-5',3'-TETRAPHOSPHATE

ChemComp-ZN:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-PGE:
TRIETHYLENE GLYCOL

ChemComp-HOH:
WATER

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-PO4:
PHOSPHATE ION

Source
  • staphylococcus aureus (strain usa300) (bacteria)
  • staphylococcus aureus subsp. aureus (bacteria)
KeywordsRNA BINDING PROTEIN / GTPase / ppGpp-binding / TRAFAC / ribosome assembly / GDP-binding

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