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Structure paper

TitleHuman Cellular Retinol Binding Protein II Forms a Domain-Swapped Trimer Representing a Novel Fold and a New Template for Protein Engineering.
Journal, issue, pagesChembiochem, Vol. 21, Page 3192-3196, Year 2020
Publish dateJan 13, 2020 (structure data deposition date)
AuthorsGhanbarpour, A. / Santos, E.M. / Pinger, C. / Assar, Z. / Hossaini Nasr, S. / Vasileiou, C. / Spence, D. / Borhan, B. / Geiger, J.H.
External linksChembiochem / PubMed:32608180
MethodsX-ray diffraction
Resolution1.67 - 3.2 Å
Structure data

PDB-6vis:
The Crystal Structure of Domain-Swapped Trimer Q108K:K40D:T53A:R58L:Q38F:Q4F:V62E Variant of HCRBPII
Method: X-RAY DIFFRACTION / Resolution: 2.79 Å

PDB-6vit:
The Crystal Structure of Apo Domain-Swapped dimer Q108K:T51D:I32C Variant of HCRBPII with an Engineered Disulfide Bond
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-6wnf:
The Crystal Structure of Apo Domain-Swapped Dimer Q108K:K40D:T53A:R58L:Q38F:Q4F:F57H Variant of HCRBPII
Method: X-RAY DIFFRACTION / Resolution: 1.67 Å

PDB-6wnj:
The Crystal Structure of Apo Domain-Swapped Trimer Q108K:T51D:A28C:I32C of HCRBPII
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-6wp0:
The Crystal Structure of Domain-Swapped Trimer Q108K:T51D variant of HCRBPII
Method: X-RAY DIFFRACTION / Resolution: 2.78 Å

PDB-6wp1:
The Crystal Structure of Apo Domain-Swapped Trimer Q108K:K40L:T51K Variant of HCRBPII
Method: X-RAY DIFFRACTION / Resolution: 2.99 Å

PDB-6wp2:
The Crystal Structure of Apo Zinc-Bound Domain Swapped-Trimer Q108K:K40D:T53A:R58L:Q38F:Q4F:F57H Variant of HCRBPII
Method: X-RAY DIFFRACTION / Resolution: 2.48 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-ACT:
ACETATE ION

ChemComp-144:
TRIS-HYDROXYMETHYL-METHYL-AMMONIUM

ChemComp-SO4:
SULFATE ION

ChemComp-ZN:
Unknown entry

Source
  • homo sapiens (human)
KeywordsLIPID BINDING PROTEIN / Domain Swapped Trimer / iLBP

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