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Structure paper

TitleStructure and mechanism of a redesigned multidrug transporter from the Major Facilitator Superfamily.
Journal, issue, pagesSci Rep, Vol. 10, Page 3949-3949, Year 2020
Publish dateFeb 10, 2020 (structure data deposition date)
AuthorsWu, H.H. / Symersky, J. / Lu, M.
External linksSci Rep / PubMed:32127561
MethodsX-ray diffraction
Resolution2 - 3 Å
Structure data

PDB-6vrz:
protein A
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-6vs0:
protein B
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-6vs1:
protein C
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-6vs2:
protein D
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-CLM:
CHLORAMPHENICOL / antibiotic*YM

ChemComp-PR:
PRASEODYMIUM ION

ChemComp-HOH:
WATER

ChemComp-DXC:
(3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID / detergent*YM

ChemComp-LDA:
LAURYL DIMETHYLAMINE-N-OXIDE / LDAO, detergent*YM

Source
  • escherichia coli (E. coli)
KeywordsTRANSPORT PROTEIN/ANTIBIOTIC / membrane protein / TRANSPORT PROTEIN-ANTIBIOTIC complex / TRANSPORT PROTEIN

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