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| Title | Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors. |
|---|---|
| Journal, issue, pages | Nat Commun, Vol. 11, Page 423-423, Year 2020 |
| Publish date | Nov 14, 2019 (structure data deposition date) |
Authors | Wang, J.X. / Irvine, M.W. / Burnell, E.S. / Sapkota, K. / Thatcher, R.J. / Li, M. / Simorowski, N. / Volianskis, A. / Collingridge, G.L. / Monaghan, D.T. ...Wang, J.X. / Irvine, M.W. / Burnell, E.S. / Sapkota, K. / Thatcher, R.J. / Li, M. / Simorowski, N. / Volianskis, A. / Collingridge, G.L. / Monaghan, D.T. / Jane, D.E. / Furukawa, H. |
External links | Nat Commun / PubMed:31969570 |
| Methods | X-ray diffraction |
| Resolution | 1.66 - 2.41 Å |
| Structure data | ![]() PDB-6uz6: ![]() PDB-6uzg: ![]() PDB-6uzr: ![]() PDB-6uzw: ![]() PDB-6uzx: |
| Chemicals | ![]() ChemComp-GLY: ![]() ChemComp-GLU: ![]() ChemComp-HOH: ![]() ChemComp-QM1: ![]() ChemComp-GOL: ![]() ChemComp-QM4: |
| Source |
|
Keywords | MEMBRANE PROTEIN / NMDAR / ligand-binding domain / agonist / antagonist |
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