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Structure paper

TitleStructural basis of HMCES interactions with abasic DNA and multivalent substrate recognition.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 26, Page 607-612, Year 2019
Publish dateJun 29, 2016 (structure data deposition date)
AuthorsHalabelian, L. / Ravichandran, M. / Li, Y. / Zeng, H. / Rao, A. / Aravind, L. / Arrowsmith, C.H.
External linksNat. Struct. Mol. Biol. / PubMed:31235913
MethodsX-ray diffraction
Resolution1.5 - 2.2 Å
Structure data

PDB-5ko9:
Crystal Structure of the SRAP Domain of Human HMCES Protein
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-6oe7:
Crystal structure of HMCES cross-linked to DNA abasic site
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-6oea:
Crystal structure of HMCES SRAP domain in complex with longer 3' overhang DNA
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-6oeb:
Crystal structure of HMCES SRAP domain in complex with 3' overhang DNA
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-UNX:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-EDO:
1,2-ETHANEDIOL

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsDNA BINDING PROTEIN / SRAP Domain / DNA-binding / Structural Genomics / Structural Genomics Consortium / SGC / DNA BINDING PROTEIN/DNA / HMCES / Protein-DNA complex / DNA damage protein / 3' overhang / DNA BINDING PROTEIN-DNA complex / DNA-protein complex / DNA-damage protein

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