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Structure paper

TitleIntracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site.
Journal, issue, pagesJ. Mol. Biol., Vol. 432, Page 1109-1125, Year 2020
Publish dateMar 20, 2019 (structure data deposition date)
AuthorsRudolph, M.J. / Czajka, T.F. / Davis, S.A. / Thi Nguyen, C.M. / Li, X.P. / Tumer, N.E. / Vance, D.J. / Mantis, N.J.
External linksJ. Mol. Biol. / PubMed:31931008
MethodsX-ray diffraction
Resolution1.732 - 2.495 Å
Structure data

PDB-6obc:
Ricin A chain bound to camelid
Method: X-RAY DIFFRACTION / Resolution: 1.762 Å

PDB-6obe:
Ricin A chain bound to VHH antibody V6H8
Method: X-RAY DIFFRACTION / Resolution: 1.732 Å

PDB-6obg:
Ricin A chain bound to VHH antibody V8E6
Method: X-RAY DIFFRACTION / Resolution: 1.996 Å

PDB-6obm:
Ricin A chain bound to VHH antibody V6A7
Method: X-RAY DIFFRACTION / Resolution: 2.495 Å

PDB-6obo:
Ricin A chain bound to VHH antibody V6A6
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-6oca:
Ricin A chain bound to VHH antibody V2G10
Method: X-RAY DIFFRACTION / Resolution: 2.113 Å

PDB-6ocd:
Ricin A chain bound to VHH antibody V6D4
Method: X-RAY DIFFRACTION / Resolution: 2.103 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

ChemComp-NI:
NICKEL (II) ION

ChemComp-IMD:
IMIDAZOLE

ChemComp-ZN:
Unknown entry

ChemComp-ACY:
ACETIC ACID

ChemComp-CA:
Unknown entry

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

Source
  • ricinus communis (castor bean)
  • vicugna pacos (alpaca)
KeywordsTOXIN

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