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-Structure paper
Title | Selectivity via Cooperativity: Preferential Stabilization of the p65/14-3-3 Interaction with Semisynthetic Natural Products. |
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Journal, issue, pages | J. Am. Chem. Soc., Vol. 142, Page 11772-11783, Year 2020 |
Publish date | Feb 4, 2019 (structure data deposition date) |
Authors | Wolter, M. / de Vink, P. / Neves, J.F. / Srdanovic, S. / Higuchi, Y. / Kato, N. / Wilson, A. / Landrieu, I. / Brunsveld, L. / Ottmann, C. |
External links | J. Am. Chem. Soc. / PubMed:32501683 |
Methods | X-ray diffraction |
Resolution | 1.13 - 1.25 Å |
Structure data | PDB-6nv2: PDB-6qhl: PDB-6qhm: |
Chemicals | ChemComp-CL: ChemComp-0V4: ChemComp-HOH: ChemComp-GOL: |
Source |
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Keywords | PEPTIDE BINDING PROTEIN / fusicoccanes / natural products / p65 / 1433 / SIGNALING PROTEIN / 14-3-3 / 14-3-3 sigma / RelA |