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Title | Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth. |
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Journal, issue, pages | Immunity, Vol. 45, Page 1108-1121, Year 2016 |
Publish date | Sep 20, 2016 (structure data deposition date) |
Authors | Huang, J. / Kang, B.H. / Ishida, E. / Zhou, T. / Griesman, T. / Sheng, Z. / Wu, F. / Doria-Rose, N.A. / Zhang, B. / McKee, K. ...Huang, J. / Kang, B.H. / Ishida, E. / Zhou, T. / Griesman, T. / Sheng, Z. / Wu, F. / Doria-Rose, N.A. / Zhang, B. / McKee, K. / O'Dell, S. / Chuang, G.Y. / Druz, A. / Georgiev, I.S. / Schramm, C.A. / Zheng, A. / Joyce, M.G. / Asokan, M. / Ransier, A. / Darko, S. / Migueles, S.A. / Bailer, R.T. / Louder, M.K. / Alam, S.M. / Parks, R. / Kelsoe, G. / Von Holle, T. / Haynes, B.F. / Douek, D.C. / Hirsch, V. / Seaman, M.S. / Shapiro, L. / Mascola, J.R. / Kwong, P.D. / Connors, M. |
External links | Immunity / PubMed:27851912 |
Methods | X-ray diffraction |
Resolution | 2.15 - 2.75 Å |
Structure data | PDB-5te4: PDB-5te6: PDB-5te7: |
Chemicals | ChemComp-NAG: ChemComp-SO4: ChemComp-BU3: ChemComp-MPD: ChemComp-HOH: ChemComp-EPE: ChemComp-EDO: |
Source |
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Keywords | IMMUNE SYSTEM / HIV-1 / VRC01-class Antibody / N6 / CD4-binding site / gp120 |