+Search query
-Structure paper
Title | MutT homologue 1 (MTH1) catalyzes the hydrolysis of mutagenic O6-methyl-dGTP. |
---|---|
Journal, issue, pages | Nucleic Acids Res., Vol. 46, Page 10888-10904, Year 2018 |
Publish date | Aug 22, 2017 (structure data deposition date) |
![]() | Jemth, A.S. / Gustafsson, R. / Brautigam, L. / Henriksson, L. / Vallin, K.S.A. / Sarno, A. / Almlof, I. / Homan, E. / Rasti, A. / Warpman Berglund, U. ...Jemth, A.S. / Gustafsson, R. / Brautigam, L. / Henriksson, L. / Vallin, K.S.A. / Sarno, A. / Almlof, I. / Homan, E. / Rasti, A. / Warpman Berglund, U. / Stenmark, P. / Helleday, T. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 0.99 - 1.8 Å |
Structure data | ![]() PDB-5otm: ![]() PDB-5otn: |
Chemicals | ![]() ChemComp-SO4: ![]() ChemComp-ACT: ![]() ChemComp-6OG: ![]() ChemComp-HOH: ![]() ChemComp-GOL: ![]() ChemComp-CA: ![]() ChemComp-EDO: ![]() ChemComp-CL: |
Source |
|
![]() | HYDROLASE / MTH1 / Inhibitor / Complex / NUDIX / Methylated nucleotide / O6-methyl-dGMP / zebrafish |