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-Structure paper
| Title | The natural product carolacton inhibits folate-dependent C1 metabolism by targeting FolD/MTHFD. |
|---|---|
| Journal, issue, pages | Nat Commun, Vol. 8, Page 1529-1529, Year 2017 |
| Publish date | May 19, 2017 (structure data deposition date) |
Authors | Fu, C. / Sikandar, A. / Donner, J. / Zaburannyi, N. / Herrmann, J. / Reck, M. / Wagner-Dobler, I. / Koehnke, J. / Muller, R. |
External links | Nat Commun / PubMed:29142318 |
| Methods | X-ray diffraction |
| Resolution | 1.89 - 2.1 Å |
| Structure data | ![]() PDB-5o22: ![]() PDB-5o28: ![]() PDB-5o2a: |
| Chemicals | ![]() ChemComp-C3R: ![]() ChemComp-HOH: |
| Source |
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Keywords | OXIDOREDUCTASE / carolacton / FolD / natural product / inhibitor |
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