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-Structure paper
Title | Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a. |
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Journal, issue, pages | Mol. Cell, Vol. 66, Page 221-233.e4, Year 2017 |
Publish date | Mar 16, 2017 (structure data deposition date) |
![]() | Swarts, D.C. / van der Oost, J. / Jinek, M. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.501 - 3.342 Å |
Structure data | ![]() PDB-5nfv: ![]() PDB-5ng6: |
Chemicals | ![]() ChemComp-MG: ![]() ChemComp-B3P: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE / CRISPR / Cas / Cpf1 / Cas12a / nuclease / genome editing / R-loop / crRNA / RuvC |