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-Structure paper
Title | 4S-Hydroxylation of Insulin at ProB28 Accelerates Hexamer Dissociation and Delays Fibrillation. |
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Journal, issue, pages | J. Am. Chem. Soc., Vol. 139, Page 8384-8387, Year 2017 |
Publish date | Jan 21, 2016 (structure data deposition date) |
Authors | Lieblich, S.A. / Fang, K.Y. / Cahn, J.K.B. / Rawson, J. / LeBon, J. / Ku, H.T. / Tirrell, D.A. |
External links | J. Am. Chem. Soc. / PubMed:28598606 |
Methods | X-ray diffraction |
Resolution | 0.97 - 2.2 Å |
Structure data | PDB-5hpr: PDB-5hpu: PDB-5hqi: PDB-5hrq: |
Chemicals | ChemComp-NA: ChemComp-GOL: ChemComp-HOH: ChemComp-IPH: ChemComp-ZN: ChemComp-CL: |
Source |
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Keywords | HORMONE / Insulin / non-canonical amino acid / hydroxyproline / non-natural amino acid / unnatural amino acid |