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-Structure paper
Title | 4S-Hydroxylation of Insulin at ProB28 Accelerates Hexamer Dissociation and Delays Fibrillation. |
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Journal, issue, pages | J. Am. Chem. Soc., Vol. 139, Page 8384-8387, Year 2017 |
Publish date | Jan 21, 2016 (structure data deposition date) |
![]() | Lieblich, S.A. / Fang, K.Y. / Cahn, J.K.B. / Rawson, J. / LeBon, J. / Ku, H.T. / Tirrell, D.A. |
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Methods | X-ray diffraction |
Resolution | 0.97 - 2.2 Å |
Structure data | ![]() PDB-5hpr: ![]() PDB-5hpu: ![]() PDB-5hqi: ![]() PDB-5hrq: |
Chemicals | ![]() ChemComp-NA: ![]() ChemComp-GOL: ![]() ChemComp-HOH: ![]() ChemComp-IPH: ![]() ChemComp-ZN: ![]() ChemComp-CL: |
Source |
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![]() | HORMONE / Insulin / non-canonical amino acid / hydroxyproline / non-natural amino acid / unnatural amino acid |