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Structure paper

TitleStructural Insights into the Allosteric Operation of the Lon AAA+ Protease
Journal, issue, pagesStructure, Vol. 24, Page 667-675, Year 2016
Publish dateMar 13, 2015 (structure data deposition date)
AuthorsLin, C.-C. / Su, S.-C. / Su, M.-Y. / Liang, P.-H. / Feng, C.-C. / Wu, S.-H. / Chang, C.-I.
External linksStructure / PubMed:27041592
MethodsX-ray diffraction
Resolution2.07 - 3.45 Å
Structure data

PDB-4ypl:
Crystal structure of a hexameric LonA protease bound to three ADPs
Method: X-RAY DIFFRACTION / Resolution: 3.45 Å

PDB-4ypn:
Crystal structure of a LonA fragment containing the 3-helix bundle and the AAA-alpha/beta domain
Method: X-RAY DIFFRACTION / Resolution: 2.07 Å

Chemicals

ChemComp-4KZ:
N-[(1R)-1-(dihydroxyboranyl)-2-phenylethyl]-Nalpha-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-HOH:
WATER

Source
  • meiothermus taiwanensis (bacteria)
KeywordsHYDROLASE / Lon protease / ADP / MMH8709 / Inhibitor / AAA+ domain / Helix-bundle / disordered

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