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Structure paper

TitleActin cytoskeleton. Mechanism of actin filament pointed-end capping by tropomodulin.
Journal, issue, pagesScience, Vol. 345, Page 463-467, Year 2014
Publish dateMay 14, 2014 (structure data deposition date)
AuthorsRao, J.N. / Madasu, Y. / Dominguez, R.
External linksScience / PubMed:25061212
MethodsX-ray diffraction
Resolution1.8 - 2.3 Å
Structure data

PDB-4pkg:
Complex of ATP-actin With the N-terminal Actin-Binding Domain of Tropomodulin
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-4pkh:
Complex of ADP-actin With the N-terminal Actin-Binding Domain of Tropomodulin
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

PDB-4pki:
Complex of ATP-actin With the C-terminal Actin-Binding Domain of Tropomodulin
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

Source
  • homo sapiens (human)
  • oryctolagus cuniculus (rabbit)
KeywordsContractile Protein/Actin-Binding Protein / Tmod / Actin Filament / Pointed-End Capping Protein / Tropomyosin / Contractile Protein / Actin-binding Protein / Contractile Protein-Actin-Binding Protein complex

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