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TitleInhibitor Sites of Unequal Affinity Linked by Binding Synergism in Mutant Forms of Recombinant Human Hexokinase Type-I
Journal, issue, pagesto be published
Publish dateMay 19, 2012 (structure data deposition date)
AuthorsShen, L. / Gao, Y. / Honzatko, R.B.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.65 - 3 Å
Structure data

PDB-4f9o:
Crystal Structure of recombinant human Hexokinase type I with 2-deoxy-Glucose 6-Phosphate
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

PDB-4foe:
Crystal Structure of recombinant human Hexokinase type I with Mannose 6-Phosphate
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-4fpb:
Crystal Structure of Recombinant Human Hexokinase Type I with 1,5-Anhydroglucitol 6-Phosphate
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-BGC:
beta-D-glucopyranose

ChemComp-0NZ:
2-deoxy-6-O-phosphono-beta-D-glucopyranose

ChemComp-NA:
Unknown entry

ChemComp-CIT:
CITRIC ACID

ChemComp-HOH:
WATER

ChemComp-M6D:
6-O-phosphono-beta-D-mannopyranose

ChemComp-0WK:
1,5-anhydro-6-O-phosphono-D-glucitol

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / hexokinase / 2-deoxy Glucose-6-Phosphate / Mannose 6-Phosphate / 1 / 5-ANHYDROGLUCITOL 6-PHOSPHATE

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