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TitleStructural Basis for Selective Recognition of Endogenous and Microbial Polysaccharides by Macrophage Receptor Sign-R1.
Journal, issue, pagesStructure, Vol. 22, Page 1595-, Year 2014
Publish dateDec 21, 2012 (structure data deposition date)
AuthorsSilva-Martin, N. / Bartual, S.G. / Rodriguez, A. / Ramirez, E. / Chacon, P. / Anthony, R.M. / Park, C.G. / Hermoso, J.A.
External linksStructure / PubMed:25450767
MethodsX-ray diffraction
Resolution1.87 - 2.6 Å
Structure data

PDB-3zhg:
Crystallographic structure of the native mouse SIGN-R1 CRD domain
Method: X-RAY DIFFRACTION / Resolution: 1.87 Å

PDB-4c9f:
Structure of SIGN-R1 in complex with Sulfodextran
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-4caj:
Crystallographic structure of the mouse SIGN-R1 CRD domain in complex with sialic acid
Method: X-RAY DIFFRACTION / Resolution: 2.191 Å

PDB-4cdh:
Crystallographic structure of the Human Igg1 alpha 2-6 sialilated Fc-Fragment
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-GQ1:
4-O-sulfo-alpha-D-glucopyranose

ChemComp-SIA:
N-acetyl-alpha-neuraminic acid

ChemComp-CL:
Unknown entry

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / C-LECTIN CRD / CAPSULAR POLYSACCHARIDE. / MEMBRANE PROTEIN / C-TYPE LECTIN / INNATE IMMUNITY / SIGN-R1 / CAPSULAR POLYSACCHARIDE / INMUNE SYSTEM

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