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TitleStructural and mutational analysis of Escherichia coli AlkB provides insight into substrate specificity and DNA damage searching.
Journal, issue, pagesPlos One, Vol. 5, Page e8680-e8680, Year 2010
Publish dateOct 30, 2009 (structure data deposition date)
AuthorsHolland, P.J. / Hollis, T.
External linksPlos One / PubMed:20084272
MethodsX-ray diffraction
Resolution2.2 - 2.9 Å
Structure data

PDB-3khb:
Crystal structure of Escherichia coli AlkB with Co(II) and 2-OG
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-3khc:
Crystal Structure of Escherichia coli AlkB in complex with ssDNA containing a 1-methylguanine lesion
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-CO:
Unknown entry

ChemComp-AKG:
2-OXOGLUTARIC ACID

ChemComp-HOH:
WATER

Source
  • escherichia coli k-12 (bacteria)
KeywordsOXIDOREDUCTASE / AlkB / 2-oxoglutarate / DNA alkylation repair / Dioxygenase / DNA damage / DNA repair / Iron / Metal-binding / oxidoreductase/DNA / 1-methylguanine / oxidoreductase-DNA complex

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