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IF

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Structure paper

TitleSmall-molecule tools for dissecting the roles of SSB/protein interactions in genome maintenance
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 107, Page 633-638, Year 2010
Publish dateMay 27, 2009 (structure data deposition date)
AuthorsLu, D. / Bernstein, D.A. / Satyshur, K.A. / Keck, J.L.
External linksProc. Natl. Acad. Sci. USA / PubMed:20018747
MethodsX-ray diffraction
Resolution1.55 - 1.6 Å
Structure data

PDB-3hl8:
Crystal structure of exonuclease I in complex with inhibitor BCBP
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

PDB-3hp9:
Crystal structure of SSB/Exonuclease I in complex with inhibitor CFAM
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-BBP:
(5R)-3-tert-butyl-1-(6-chloro-1,3-benzothiazol-2-yl)-4,5-dihydro-1H-pyrazol-5-ol

ChemComp-DMS:
DIMETHYL SULFOXIDE / DMSO, precipitant*YM

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

ChemComp-CF1:
2-{[2-chloro-5-(trifluoromethyl)phenyl]amino}-5-methoxybenzoic acid

Source
  • escherichia coli (E. coli)
KeywordsHYDROLASE / EXONUCLEASE / SSB / GENOME MAINTENANCE / DNA DAMAGE / DNA REPAIR / Nuclease

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