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Structure paper

TitleCrystal structure of iodotyrosine deiodinase, a novel flavoprotein responsible for iodide salvage in thyroid glands.
Journal, issue, pagesJ. Biol. Chem., Vol. 284, Page 19659-19667, Year 2009
Publish dateFeb 18, 2009 (structure data deposition date)
AuthorsThomas, S.R. / McTamney, P.M. / Adler, J.M. / Laronde-Leblanc, N. / Rokita, S.E.
External linksJ. Biol. Chem. / PubMed:19436071
MethodsX-ray diffraction
Resolution2 - 2.61 Å
Structure data

PDB-3gb5:
Crystal structure of Mus musculus iodotyrosine deiodinase (IYD) bound to FMN
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-3gfd:
Crystal structure of Mus musculus iodotyrosine deiodinase (IYD) bound to FMN and mono-iodotyrosine (MIT)
Method: X-RAY DIFFRACTION / Resolution: 2.45 Å

PDB-3gh8:
Crystal structure of Mus musculus iodotyrosine deiodinase (IYD) bound to FMN and di-iodotyrosine (DIT)
Method: X-RAY DIFFRACTION / Resolution: 2.61 Å

Chemicals

ChemComp-FMN:
FLAVIN MONONUCLEOTIDE

ChemComp-PO4:
PHOSPHATE ION

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

ChemComp-IYR:
3-IODO-TYROSINE / hormone*YM

ChemComp-GOL:
GLYCEROL

ChemComp-TYI:
3,5-DIIODOTYROSINE / hormone*YM

Source
  • mus musculus (house mouse)
KeywordsOXIDOREDUCTASE / IYD / iodide salvage / flavoprotein / FMN / Membrane / NADP / Transmembrane / mono-iodotyrosine / MIT / di-iodotyrosine / DIT

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