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-Structure paper
Title | The structural basis of Cryptosporidium -specific IMP dehydrogenase inhibitor selectivity |
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Journal, issue, pages | J. Am. Chem. Soc., Vol. 132, Page 1230-1231, Year 2010 |
Publish date | Dec 4, 2008 (structure data deposition date) |
![]() | Macpherson, I.S. / Kirubakaran, S. / Gorla, S.K. / Riera, T.V. / D'Aquino, J.A. / Zhang, M. / Cuny, G.D. / Hedstrom, L. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.8 - 3.19 Å |
Structure data | ![]() PDB-3ffs: ![]() PDB-3khj: |
Chemicals | ![]() ChemComp-IMP: ![]() ChemComp-C64: ![]() ChemComp-ACT: ![]() ChemComp-HOH: |
Source |
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![]() | OXIDOREDUCTASE / beta-alpha barrel / TIM fold / enzyme-inhibitor complex |