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Structure paper

TitleStructural basis of UV DNA-damage recognition by the DDB1-DDB2 complex.
Journal, issue, pagesCell(Cambridge,Mass. ), Vol. 135, Page 1213-1223, Year 2008
Publish dateSep 15, 2008 (structure data deposition date)
AuthorsScrima, A. / Konickova, R. / Czyzewski, B.K. / Kawasaki, Y. / Jeffrey, P.D. / Groisman, R. / Nakatani, Y. / Iwai, S. / Pavletich, N.P. / Thoma, N.H.
External linksCell(Cambridge,Mass. ) / PubMed:19109893
MethodsX-ray diffraction
Resolution2.3 - 3.3 Å
Structure data

PDB-3ei1:
Structure of hsDDB1-drDDB2 bound to a 14 bp 6-4 photoproduct containing DNA-duplex
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-3ei2:
Structure of hsDDB1-drDDB2 bound to a 16 bp abasic site containing DNA-duplex
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-3ei3:
Structure of the hsDDB1-drDDB2 complex
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-3ei4:
Structure of the hsDDB1-hsDDB2 complex
Method: X-RAY DIFFRACTION / Resolution: 3.3 Å

Chemicals

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • danio rerio (zebrafish)
KeywordsDNA BINDING PROTEIN/DNA / UV-damage / DDB / nucleotide excision repair / xeroderma pigmentosum / Alternative splicing / Disease mutation / DNA damage / DNA repair / DNA-binding / Nucleus / Phosphoprotein / Polymorphism / WD repeat / Ubl conjugation pathway / DNA BINDING PROTEIN-DNA COMPLEX / DNA BINDING PROTEIN / Cytoplasm / Host-virus interaction / UV-damage; DDB

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