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-Structure paper
Title | Crystal structures of the N-terminal kinase domain of human RSK1 bound to three different ligands: Implications for the design of RSK1 specific inhibitors. |
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Journal, issue, pages | Protein Sci., Vol. 16, Page 2626-2635, Year 2007 |
Publish date | Aug 28, 2007 (structure data deposition date) |
Authors | Ikuta, M. / Kornienko, M. / Byrne, N. / Reid, J.C. / Mizuarai, S. / Kotani, H. / Munshi, S.K. |
External links | Protein Sci. / PubMed:17965187 |
Methods | X-ray diffraction |
Resolution | 2 - 2.1 Å |
Structure data | PDB-2z7q: PDB-2z7r: PDB-2z7s: |
Chemicals | ChemComp-MG: ChemComp-ACP: ChemComp-HOH: ChemComp-STU: ChemComp-P01: |
Source |
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Keywords | TRANSFERASE / protein kinase; cancer; kinase inhibitor / ATP-binding / Magnesium / Metal-binding / Nucleotide-binding / Phosphorylation / Serine/threonine-protein kinase / protein kinase / cancer / kinase inhibitor / Polymorphism |