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Structure paper

TitleCrystal structures and catalytic mechanism of cytochrome P450 StaP that produces the indolocarbazole skeleton
Journal, issue, pagesProc. Natl. Acad. Sci. Usa, Vol. 104, Page 11591-11596, Year 2007
Publish dateJun 6, 2007 (structure data deposition date)
AuthorsMakino, M. / Sugimoto, H. / Shiro, Y. / Asamizu, S. / Onaka, H. / Nagano, S.
External linksProc. Natl. Acad. Sci. Usa / PubMed:17606921
MethodsX-ray diffraction
Resolution1.9 - 2.4 Å
Structure data

PDB-2z3t:
Crystal Structure of Substrate Free Cytochrome P450 StaP (CYP245A1)
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-2z3u:
Crystal Structure of Chromopyrrolic Acid Bound Cytochrome P450 StaP (CYP245A1)
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

ChemComp-IMD:
IMIDAZOLE

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

ChemComp-CRR:
3,4-DI-1H-INDOL-3-YL-1H-PYRROLE-2,5-DICARBOXYLIC ACID

Source
  • streptomyces sp. tp-a0274 (bacteria)
KeywordsOXIDOREDUCTASE / cytochrome P450 / monoxygenase / oxydoreductase / heme-enzyme / chromopyrrolic acid

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