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| Title | Structural characterizations of nonpeptidic thiadiazole inhibitors of matrix metalloproteinases reveal the basis for stromelysin selectivity. |
|---|---|
| Journal, issue, pages | Protein Sci., Vol. 7, Page 2118-2126, Year 1998 |
| Publish date | Jun 9, 1998 (structure data deposition date) |
Authors | Finzel, B.C. / Baldwin, E.T. / Bryant Jr., G.L. / Hess, G.F. / Wilks, J.W. / Trepod, C.M. / Mott, J.E. / Marshall, V.P. / Petzold, G.L. / Poorman, R.A. ...Finzel, B.C. / Baldwin, E.T. / Bryant Jr., G.L. / Hess, G.F. / Wilks, J.W. / Trepod, C.M. / Mott, J.E. / Marshall, V.P. / Petzold, G.L. / Poorman, R.A. / O'Sullivan, T.J. / Schostarez, H.J. / Mitchell, M.A. |
External links | PubMed:9792098 |
| Methods | X-ray diffraction |
| Resolution | 1.8 - 2.2 Å |
| Structure data | ![]() PDB-1usn: ![]() PDB-2usn: |
| Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-CA: ![]() ChemComp-IN9: ![]() ChemComp-HOH: ![]() ChemComp-IN8: |
| Source |
|
Keywords | HYDROLASE / METALLOPROTEASE / FIBROBLAST / COLLAGEN DEGRADATION |
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homo sapiens (human)
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