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Structure paper

TitleStructural basis of charge transfer complex formation by riboflavin bound to 6,7-dimethyl-8-ribityllumazine synthase
Journal, issue, pagesEur. J. Biochem., Vol. 271, Page 3208-3214, Year 2004
Publish dateJun 30, 2005 (structure data deposition date)
AuthorsKoch, M. / Breithaupt, C. / Gerhardt, S. / Haase, I. / Weber, S. / Cushman, M. / Huber, R. / Bacher, A. / Fischer, M.
External linksEur. J. Biochem. / PubMed:15265040
MethodsX-ray diffraction
Resolution2.7 - 2.8 Å
Structure data

PDB-2a57:
Structure of 6,7-Dimthyl-8-ribityllumazine synthase from Schizosaccharomyces pombe mutant W27Y with bound ligand 6-carboxyethyl-7-oxo-8-ribityllumazine
Method: X-RAY DIFFRACTION / Resolution: 2.75 Å

PDB-2a58:
Structure of 6,7-Dimethyl-8-ribityllumazine synthase from Schizosaccharomyces pombe mutant W27Y with bound riboflavin
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-2a59:
Structure of 6,7-Dimethyl-8-ribityllumazine synthase from Schizosaccharomyces pombe mutant W27Y with bound ligand 5-nitroso-6-ribitylamino-2,4(1H,3H)-pyrimidinedione
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-CRM:
3-[8-((2S,3S,4R)-2,3,4,5-TETRAHYDROXYPENTYL)-2,4,7-TRIOXO-1,3,8-TRIHYDROPTERIDIN-6-YL]PROPANOIC ACID

ChemComp-PO4:
PHOSPHATE ION

ChemComp-RBF:
RIBOFLAVIN

ChemComp-HOH:
WATER

ChemComp-LMZ:
5-NITROSO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE

Source
  • schizosaccharomyces pombe (fission yeast)
KeywordsTRANSFERASE / 6 / 7-dimethyl-8-ribityllumazine synthase / riboflavin / riboflavin biosynthesis / LUSY / Schizosaccharomyces pombe / mutant W27Y / 5-nitroso-6-ribitylamino-2 / 4(1H / 3H)-pyrimidinedione

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