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Structure paper

TitleCrystal structures of human mitochondrial branched chain aminotransferase reaction intermediates: ketimine and pyridoxamine phosphate forms
Journal, issue, pagesBiochemistry, Vol. 41, Page 11592-11601, Year 2002
Publish dateJan 15, 2002 (structure data deposition date)
AuthorsYennawar, N.H. / Conway, M.E. / Yennawar, H.P. / Farber, G.K. / Hutson, S.M.
External linksBiochemistry / PubMed:12269802
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-1kt8:
HUMAN BRANCHED CHAIN AMINO ACID AMINOTRANSFERASE (MITOCHONDRIAL): THREE DIMENSIONAL STRUCTURE OF ENZYME IN ITS KETIMINE FORM WITH THE SUBSTRATE L-ISOLEUCINE
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-1kta:
HUMAN BRANCHED CHAIN AMINO ACID AMINOTRANSFERASE : THREE DIMENSIONAL STRUCTURE OF THE ENZYME IN ITS PYRIDOXAMINE PHOSPHATE FORM.
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-ILP:
N-[O-PHOSPHONO-PYRIDOXYL]-ISOLEUCINE

ChemComp-ACY:
ACETIC ACID

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-PMP:
4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE

ChemComp-KIV:
3-METHYL-2-OXOBUTANOIC ACID

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / FOLD TYPE IV

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