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Structure paper

TitleSimultaneous Binding of Ptdins(4,5)P2 and Clathrin by Ap180 in the Nucleation of Clathrin Lattices on Membranes
Journal, issue, pagesScience, Vol. 291, Page 1051-, Year 2001
Publish dateNov 30, 2000 (structure data deposition date)
AuthorsFord, M.G.J. / Pearse, B.M.F. / Higgins, M.K. / Vallis, Y. / Owen, D.J. / Gibson, A. / Hopkins, C.R. / Evans, P.R. / Mcmahon, H.T.
External linksScience / PubMed:11161218
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-1hf8:
CALM-N N-terminal domain of clathrin assembly lymphoid myeloid leukaemia protein
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-1hfa:
CALM-N N-terminal domain of clathrin assembly lymphoid myeloid leukaemia protein, PI(4,5)P2 complex
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-1hg2:
CALM-N N-terminal domain of clathrin assembly lymphoid myeloid leukaemia protein, Inositol(4,5)P2 complex
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-1hg5:
CALM-N N-terminal domain of clathrin assembly lymphoid myeloid leukaemia protein, inositol(1,2,3,4,5,6)P6 complex
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-PIO:
[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate

ChemComp-IP2:
D-MYO-INOSITOL-4,5-BISPHOSPHATE

ChemComp-IHP:
INOSITOL HEXAKISPHOSPHATE

Source
  • rattus norvegicus (Norway rat)
KeywordsCLATHRIN / TRISKELION / COATED VESICLES / ENDOCYTOSIS / SELF-ASSEMBLY / ALPHA-ALPHA SUPERHELIX / ADAPTOR

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