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Structure paper

TitleThe structure and mechanism of the type II dehydroquinase from Streptomyces coelicolor.
Journal, issue, pagesStructure, Vol. 10, Page 493-503, Year 2002
Publish dateSep 10, 1999 (structure data deposition date)
AuthorsRoszak, A.W. / Robinson, D.A. / Krell, T. / Hunter, I.S. / Fredrickson, M. / Abell, C. / Coggins, J.R. / Lapthorn, A.J.
External linksStructure / PubMed:11937054
MethodsX-ray diffraction
Resolution1.6 - 2 Å
Structure data

PDB-1d0i:
CRYSTAL STRUCTURE OF TYPE II DEHYDROQUINASE FROM STREPTOMYCES COELICOLOR COMPLEXED WITH PHOSPHATE IONS
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-1gtz:
Structure of STREPTOMYCES COELICOLOR TYPE II DEHYDROQUINASE R23A MUTANT IN COMPLEX WITH DEHYDROSHIKIMATE
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-1gu0:
CRYSTAL STRUCTURE OF TYPE II DEHYDROQUINASE FROM STREPTOMYCES COELICOLOR
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-1gu1:
Crystal structure of type II dehydroquinase from Streptomyces coelicolor complexed with 2,3-anhydro-quinic acid
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-HOH:
WATER

ChemComp-DHK:
3-DEHYDROSHIKIMATE

ChemComp-FA1:
2,3 -ANHYDRO-QUINIC ACID

ChemComp-GOL:
GLYCEROL

ChemComp-TLA:
L(+)-TARTARIC ACID

Source
  • streptomyces coelicolor (bacteria)
KeywordsLYASE / TYPE II DEHYDROQUINASE / SHIKIMATE PATHWAY / DODECAMERIC QUATERNARY STRUCTURE / TETRAHEDRAL SYMMETRY / TETRAHEDRAL SYMMETRY AROMATIC AMINO ACID BIOSYNTHESIS

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