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Structure paper

TitleGhost neuron unlocks in situ high-resolution structural mapping of intracellular architecture in neurons
Journal, issue, pagesTo Be Published
Publish dateJun 5, 2025 (structure data deposition date)
AuthorsBodakuntla S / Marelli J / Vasquez-Montes V / Biertumpfel C / Mizuno N
External linksSearch PubMed
MethodsEM (helical sym.)
Resolution3.24 - 5.32 Å
Structure data

EMDB-71056: In situ cryo-EM structure of axonal cofilactin filaments from ghost neurons
Method: EM (helical sym.) / Resolution: 5.32 Å

76716

12rt

EMDB-76716, PDB-12rt:
In situ cryo-EM structure of axonal microtubules from ghost neurons (compact lattice)
Method: EM (helical sym.) / Resolution: 3.96 Å

76717

12ru

EMDB-76717, PDB-12ru:
In situ cryo-EM structure of axonal microtubules from ghost neurons (expanded lattice)
Method: EM (helical sym.) / Resolution: 3.66 Å

76718

12rv

EMDB-76718, PDB-12rv:
In situ cryo-EM structure of axonal F-actin from ghost neurons
Method: EM (helical sym.) / Resolution: 3.24 Å

Chemicals

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsSTRUCTURAL PROTEIN / cytoskeleton / microtubules / neuron / axon / F-actin

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