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-Structure paper
| Title | Cryo-EM structure of ALK in complex with CRBN/DDB1 and TRI-611 |
|---|---|
| Journal, issue, pages | To Be Published |
| Publish date | Aug 27, 2025 (structure data deposition date) |
Authors | Bart AG / Kamadurai HB |
External links | Search PubMed |
| Methods | EM (single particle) |
| Resolution | 2.7 - 2.8 Å |
| Structure data | EMDB-72353, PDB-9xzg: ![]() EMDB-72684: ALK focused cryo-EM map of TRI-611:ALK:CRBN/DDB1 ![]() EMDB-72685: Composite cryo-EM density map of TRI-611:ALK:CRBN:DDB1 |
| Chemicals | ![]() ChemComp-ZN: ![]() PDB-1crm: |
| Source |
|
Keywords | LIGASE / DNA Binding Protein-Transferase Complex / DNA BINDING PROTEIN / Ternary Complex / Molecular Glue |
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homo sapiens (human)
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