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TitleStructural insights into the recruitment of viral Type 2 IRES to ribosomal preinitiation complex for protein synthesis
Journal, issue, pagesElife, Year 2026
Publish dateMay 16, 2025 (structure data deposition date)
AuthorsDas D / Hussain T
External linksElife / Search PubMed
MethodsEM (single particle)
Resolution4.5 - 5.01 Å
Structure data

64644

9uzk

EMDB-64644, PDB-9uzk:
EMCV IRES captured on mammalian 40S with initiator tRNA
Method: EM (single particle) / Resolution: 4.6 Å

64645

9uzl

EMDB-64645, PDB-9uzl:
EMCV IRES captured on mammalian 40S ribosome with initiator tRNA and eIF2
Method: EM (single particle) / Resolution: 5.01 Å

64646

9uzm

EMDB-64646, PDB-9uzm:
40S ribosome without initiation factors
Method: EM (single particle) / Resolution: 4.5 Å

Source
  • oryctolagus cuniculus (rabbit)
  • encephalomyocarditis virus
KeywordsRIBOSOME / EMCV IRES / 40S ribosome / 48S PIC

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