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Structure paper

TitleStructures of EHD2 filaments on curved membranes provides a model for caveolar neck stabilization
Journal, issue, pagesbiorxiv. org, Year 2025
Publish dateMay 27, 2025 (structure data deposition date)
AuthorsVazquez-Sarandeses E / Mikirtumov V / Noel J / Kudryashev M / Daumke O
External linksbiorxiv. org / Search PubMed
MethodsEM (subtomogram averaging)
Resolution6.7 Å
Structure data

53909
EMDB Unreleased entry

9rbu

EMDB-53909, PDB-9rbu:
Cryo-ET structure of full-length membrane-bound EHD2 complex
Method: EM (subtomogram averaging) / Resolution: 6.7 Å

Chemicals

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

Source
  • mus musculus (house mouse)
KeywordsSTRUCTURAL PROTEIN / Eps15-homology domain-containing proteins (EHDs) / dynamin-related ATPases / membrane remodeling / human myotubes / membrane repair process / caveolae / EHD2 / lipid homeostasis / plasma membrane invaginations / oligomer / nucleotide binding / EHD2-dependent caveolae stabilization / GTPase (G-) domain / ATPase activity / liposome tubulation

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