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TitleSerial amplification of tau filaments using Alzheimers brain homogenates and C322A or C322S recombinant tau
Journal, issue, pagesTo Be Published
Publish dateApr 30, 2025 (structure data deposition date)
AuthorsSantambrogio A / Lovestam S / Metrick AM / Lohr ST / Xu P / Caughey B / Scheres HWS / Vendruscolo M
External linksSearch PubMed
MethodsEM (helical sym.)
Resolution2.6 - 2.8 Å
Structure data

53527

9r2f

EMDB-53527, PDB-9r2f:
Tau filaments seeded by AD homogenate using 0N3R C322A
Method: EM (helical sym.) / Resolution: 2.8 Å

53530

9r2h

EMDB-53530, PDB-9r2h:
Tau filaments seeded by AD homogenate using 0N3R C322S
Method: EM (helical sym.) / Resolution: 2.6 Å

Source
  • homo sapiens (human)
KeywordsPROTEIN FIBRIL / MAPT / Tau / Alzheimer's Disease / RT-QuiC

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