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| Title | Structural and biophysical insights into targeting of claudin-4 by a synthetic antibody fragment |
|---|---|
| Journal, issue, pages | Commun Biol, Vol. 7, Page 733, Year 2024 |
| Publish date | Sep 11, 2023 (structure data deposition date) |
Authors | Erramilli SK / Dominik PK / Ogbu CP / Kossiakoff AA / Vecchio AJ |
External links | Commun Biol / Search PubMed |
| Methods | EM (single particle) |
| Resolution | 2.54 - 5.3 Å |
| Structure data | ![]() EMDB-41897: Cryo-EM structure of human claudin-4 complex with Clostridium perfringens enterotoxin C-terminal domain, sFab COP-1, and Nanobody (Tight Mask) EMDB-41899: Cryo-EM structure of human claudin-4 complex with Clostridium perfringens enterotoxin C-terminal domain, sFab COP-1, and Nanobody (Loose Mask) EMDB-41915, PDB-8u5b: |
| Chemicals | ![]() ChemComp-AV0: ![]() ChemComp-HOH: |
| Source |
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Keywords | MEMBRANE PROTEIN / Claudin / Fab / Toxin / Nanobody |
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