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-Structure paper
Title | Structural basis of LRPPRC-SLIRP-dependent translation by the mitoribosome |
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Journal, issue, pages | To Be Published |
Publish date | Aug 6, 2022 (structure data deposition date) |
Authors | Singh V / Conor J / Itoh Y / Soto T / Fontanesi F / Couvillian M / Huynen M / Churchman S / Barrientos A / Amunts A |
External links | Search PubMed |
Methods | EM (single particle) |
Resolution | 2.69 - 3.38 Å |
Structure data | EMDB-15544, PDB-8any: EMDB-16407: Human mitochondrial ribosome in complex with LRPPRC-SLIRP, A-site, P-site, E-site tRNAs and mRNA (focussed on SSU head) EMDB-16408: Human mitochondrial ribosome in complex with LRPPRC-SLIRP, A-site, P-site, E-site tRNAs and mRNA (focussed on SSU body) EMDB-16409: Human mitochondrial ribosome in complex with LRPPRC-SLIRP, A-site, P-site, E-site tRNAs and mRNA (masked refined on SSU tail) EMDB-16410: Human mitochondrial ribosome in complex with LRPPRC-SLIRP, A-site, P-site, E-site tRNAs and mRNA (focussed on LSU body) EMDB-16411: Human mitochondrial ribosome in complex with LRPPRC-SLIRP, A-site, P-site, E-site tRNAs and mRNA (focussed on L10/L12 stalk) EMDB-16412: Human mitochondrial ribosome in complex with LRPPRC-SLIRP, A-site, P-site, E-site tRNAs and mRNA (focussed on mS39-LRPPRC-SLIRP) EMDB-16413: Human mitochondrial ribosome in complex with LRPPRC-SLIRP, A-site, P-site, E-site tRNAs and mRNA (focussed on central protuberance) EMDB-16414: Human mitochondrial ribosome in complex with LRPPRC-SLIRP, A-site, P-site, E-site tRNAs and mRNA (consensus) |
Chemicals | ChemComp-NAD: ChemComp-SPM: ChemComp-SPD: ChemComp-MG: ChemComp-K: ChemComp-ZN: ChemComp-FES: ChemComp-ATP: ChemComp-GDP: ChemComp-PUT: ChemComp-VAL: ChemComp-HOH: |
Source |
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Keywords | RIBOSOME / mitochondrial translation / mRNA delivery |