EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L
ジャーナル・号・ページ	To Be Published
掲載日	2023年10月31日 (構造データの登録日)
著者	Benoit MPMH / Rao L / Asenjo AB / Gennerich A / Sosa H
リンク	PubMedで検索
手法	EM (らせん対称)
解像度	2.7 - 3.4 Å
構造データ	42543 8utn EMDB-42543, PDB-8utn: KIF1A[1-393] AMP-PNP bound two-heads-bound state in complex with a microtubule (class T23L1) 手法: EM (らせん対称) / 解像度: 3.1 Å 42544 8uto EMDB-42544, PDB-8uto: KIF1A[1-393] AMP-PNP bound two-heads-bound state in complex with a microtubule - class T2L1 手法: EM (らせん対称) / 解像度: 3.2 Å 42545 8utp EMDB-42545, PDB-8utp: KIF1A[1-393] - AMP-PNP two-heads-bound state in complex with a microtubule - class T3L1 手法: EM (らせん対称) / 解像度: 3.2 Å 42546 8utq EMDB-42546, PDB-8utq: KIF1A[1-393] AMP-PNP bound one-head-bound state in complex with a microtubule - class T1L02* 手法: EM (らせん対称) / 解像度: 3.1 Å 42547 8utr EMDB-42547, PDB-8utr: KIF1A[1-393] ADP bound in complex with a microtubule 手法: EM (らせん対称) / 解像度: 3.3 Å 42548 8uts EMDB-42548, PDB-8uts: KIF1A[1-393] APO in complex with a microtubule 手法: EM (らせん対称) / 解像度: 2.7 Å 42549 8utt EMDB-42549, PDB-8utt: KIF1A[1-393] P305L mutant AMP-PNP bound two-heads-bound state in complex with a microtubule 手法: EM (らせん対称) / 解像度: 3.1 Å 42550 8utu EMDB-42550: KIF1A[1-393] AMP-PNP bound one-head-bound state in complex with a microtubule - class T1L02* PDB-8utu: KIF1A[1-393] P305L mutant AMP-PNP bound one and two heads bound states merged, in complex with a microtubule 手法: EM (らせん対称) / 解像度: 3.0 Å 42551 8utv EMDB-42551, PDB-8utv: KIF1A[1-393] P305L mutant ADP bound in complex with a microtubule 手法: EM (らせん対称) / 解像度: 3.0 Å 42552 8utw EMDB-42552, PDB-8utw: KIF1A[1-393] P305L mutant APO in complex with a microtubule 手法: EM (らせん対称) / 解像度: 3.4 Å 42553 8uty EMDB-42553, PDB-8uty: KIF1A[1-393] P364L mutant AMP-PNP bound two-heads-bound state in complex with a microtubule 手法: EM (らせん対称) / 解像度: 3.3 Å
化合物	ChemComp-MG: Unknown entry / マグネシウムジカチオン ChemComp-ANP: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / AMP-PNP / AMP-PNP, エネルギー貯蔵分子類似体YM ChemComp-GTP: GUANOSINE-5'-TRIPHOSPHATE / GTP / GTP, エネルギー貯蔵分子YM ChemComp-GDP: GUANOSINE-5'-DIPHOSPHATE / GDP / GDP, エネルギー貯蔵分子YM ChemComp-TA1: TAXOL / パクリタキセル / 薬剤, 化学療法薬YM ChemComp-ADP: ADENOSINE-5'-DIPHOSPHATE / ADP / ADP, エネルギー貯蔵分子*YM
由来	homo sapiens (ヒト) sus scrofa (ブタ)
キーワード	MOTOR PROTEIN / KIF1A / kinesin / motility / microtubule / tubulin