タイトル | Polyketide Trimming Shapes Dihydroxynaphthalene-Melanin and Anthraquinone Pigments. |
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ジャーナル・号・ページ | Adv Sci, Vol. 11, Page e2400184-e2400184, Year 2024 |
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掲載日 | 2023年8月24日 (構造データの登録日) |
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著者 | Schmalhofer, M. / Vagstad, A.L. / Zhou, Q. / Bode, H.B. / Groll, M. |
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リンク | Adv Sci / PubMed:38491909 |
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手法 | X線回折 |
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解像度 | 1.55 - 2.05 Å |
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構造データ | PDB-8qbh: AntI in complex with 1-Naphthol 手法: X-RAY DIFFRACTION / 解像度: 2.05 Å PDB-8qbi: AntI in closed state 手法: X-RAY DIFFRACTION / 解像度: 1.55 Å PDB-8qd1: Ayg1p from A. fumigatus catalyzes polyketide shortening in the biosynthesis of DHN-melanin 手法: X-RAY DIFFRACTION / 解像度: 1.7 Å PDB-8qd2: Ayg1p in complex with 1,3-Dihydroxynaphthalene 手法: X-RAY DIFFRACTION / 解像度: 1.75 Å PDB-8qd3: Ayg1p in complex with 1,3,6,8-Tetrahydroxynaphthalene 手法: X-RAY DIFFRACTION / 解像度: 1.7 Å PDB-8qd4: Ayg1p active site converted to tetrahedral sulfonate ester 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-8qd5: AntI Ser245DHA (PSF) 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-8qd6: AntI Ser245DHA (PMSF) 手法: X-RAY DIFFRACTION / 解像度: 1.7 Å PDB-8qd7: Wdyg1p from W. dermatitidis catalyzes polyketide shortening in the biosynthesis of DHN-melanin 手法: X-RAY DIFFRACTION / 解像度: 1.85 Å PDB-8qd8: Wdyg1p in complex with 1,3-Dihydroxynaphthalene 手法: X-RAY DIFFRACTION / 解像度: 1.65 Å PDB-8qd9: Wdyg1p in complex with 1,3,6,8-Tetrahydroxynaphthalene 手法: X-RAY DIFFRACTION / 解像度: 1.95 Å PDB-8qda: Wdyg1p Ser256DHA (PMSF) 手法: X-RAY DIFFRACTION / 解像度: 1.85 Å PDB-8qdb: Wdyg1p Ser256DHA (PSF) 手法: X-RAY DIFFRACTION / 解像度: 1.85 Å |
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化合物 | |
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由来 | photorhabdus laumondii subsp. laumondii tto1 (バクテリア)![](img/tx_fungus.gif) aspergillus fumigatus (カビ) exophiala dermatitidis (菌類)
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キーワード | LYASE / Natural Product Biosynthesis / Polyketide Synthase System / alpha / beta-Hydrolase Fold / Polyketide Shortening / Retro Claisen Reaction |
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