EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	The Molecular Basis of Catalysis by SDR Family Members Ketoacyl-ACP Reductase FabG and Enoyl-ACP Reductase FabI in Type-II Fatty Acid Biosynthesis.
ジャーナル・号・ページ	Angew. Chem. Int. Ed. Engl., Vol. 62, Page e202313109-e202313109, Year 2023
掲載日	2023年5月17日 (構造データの登録日)
著者	Zhou, J. / Zhang, L. / Wang, Y. / Song, W. / Huang, Y. / Mu, Y. / Schmitz, W. / Zhang, S.Y. / Lin, H. / Chen, H.Z. / Ye, F.
リンク	Angew. Chem. Int. Ed. Engl. / PubMed:37779101
手法	X線回折
解像度	1.8 - 2.83 Å
構造データ	PDB-8jf9: Crystal structure of 3-oxoacyl-ACP reductase FabG from Helicobacter pylori 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-8jfa: Crystal structure of 3-oxoacyl-ACP reductase FabG in complex with NADPH from Helicobacter pylori 手法: X-RAY DIFFRACTION / 解像度: 2.55 Å PDB-8jfg: Crystal structure of 3-oxoacyl-ACP reductase FabG in complex with NADP+ and 3-keto-octanoyl-ACP from Helicobacter pylori 手法: X-RAY DIFFRACTION / 解像度: 2.83 Å PDB-8jfh: Crystal structure of 3-oxoacyl-ACP reductase FabG in complex with NADP+ and 3-keto-octanoyl-ACP from Helicobacter pylori in an inactive form that priors the acyl substrate delivery 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-8jfi: Crystal structure of 3-oxoacyl-ACP reductase FabG in complex with NADP+ and 3-keto-hexanoyl-ACP from Helicobacter pylori 手法: X-RAY DIFFRACTION / 解像度: 2.38 Å PDB-8jfj: Crystal structure of enoyl-ACP reductase FabI from Helicobacter pylori 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-8jfm: Crystal structure of enoyl-ACP reductase FabI in complex with NADH from Helicobacter pylori 手法: X-RAY DIFFRACTION / 解像度: 2.21 Å PDB-8jfn: Crystal structure of enoyl-ACP reductase FabI in complex with NAD+ and crotonyl-ACP from Helicobacter pylori 手法: X-RAY DIFFRACTION / 解像度: 2.41 Å
化合物	ChemComp-HOH: WATER ChemComp-NAP: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE ChemComp-UHC: ~{S}-[2-[3-[[(2~{S})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] 3-oxidanylideneoctanethioate ChemComp-PN7: N~3~-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-(2-sulfanylethyl)-beta-alaninamide ChemComp-NAD: NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NADYM ChemComp-PSR*: THIOBUTYRIC ACID S-{2-[3-(2-HYDROXY-3,3-DIMETHYL-4-PHOSPHONOOXY-BUTYRYLAMINO)-PROPIONYLAMINO]-ETHYL} ESTER
由来	helicobacter pylori (ピロリ菌)
キーワード	BIOSYNTHETIC PROTEIN / 3-oxoacyl-ACP reductase / FabG / Helicobacter pylori / NADPH / NADP+ / 3-keto-octanoyl-ACP / 3-keto-hexanoyl-ACP / enoyl-ACP reductase / FabI / NADH / NAD+ / crotonyl-ACP