タイトル | Structures of Fission Yeast Inositol Pyrophosphate Kinase Asp1 in Ligand-Free, Substrate-Bound, and Product-Bound States. |
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ジャーナル・号・ページ | Mbio, Vol. 13, Page e0308722-e0308722, Year 2022 |
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掲載日 | 2022年8月10日 (構造データの登録日) |
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著者 | Benjamin, B. / Goldgur, Y. / Jork, N. / Jessen, H.J. / Schwer, B. / Shuman, S. |
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リンク | Mbio / PubMed:36468882 |
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手法 | X線回折 |
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解像度 | 1.6 - 2 Å |
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構造データ | PDB-8e1h: Asp1 kinase in complex with ADP Mg 5-IP7 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-8e1i: Asp1 kinase in complex with ATP Mg 5-IP7 手法: X-RAY DIFFRACTION / 解像度: 2 Å PDB-8e1j: Asp1 kinase in complex with 1,5-IP8 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å PDB-8e1s: Asp1 kinase in complex with ADPNP Mn IP6 手法: X-RAY DIFFRACTION / 解像度: 1.72 Å PDB-8e1t: Asp1 kinase in complex with ADPNP Mg IP7 手法: X-RAY DIFFRACTION / 解像度: 1.71 Å PDB-8e1v: Asp1 kinase in complex with ADPNP Mg IP6 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å |
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化合物 | ChemComp-I7P: (1r,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate / D-myo-イノシト-ル1,2,3,4,6-ペンタキスりん酸5-二りん酸
ChemComp-I8P: (1R,3S,4R,5S,6R)-2,4,5,6-tetrakis(phosphonooxy)cyclohexane-1,3-diyl bis[trihydrogen (diphosphate)] / D-myo-イノシト-ル2,3,4,6-テトラキスりん酸1,5-ビス二りん酸
ChemComp-ANP: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / AMP-PNP / AMP-PNP, エネルギー貯蔵分子類似体*YM
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由来 | - schizosaccharomyces pombe (分裂酵母)
- schizosaccharomyces pombe/puccinia graminis mixed dna library (分裂酵母)
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キーワード | TRANSFERASE / Inositol pyrophosphosphate IPP kinase Fission yeast |
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