EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions.
ジャーナル・号・ページ	J. Am. Chem. Soc., Vol. 143, Page 8454-8464, Year 2021
掲載日	2020年10月14日 (構造データの登録日)
著者	Cossar, P.J. / Wolter, M. / van Dijck, L. / Valenti, D. / Levy, L.M. / Ottmann, C. / Brunsveld, L.
リンク	J. Am. Chem. Soc. / PubMed:34047554
手法	X線回折
解像度	1.081 - 1.9 Å
構造データ	PDB-7aog: 14-3-3 sigma in complex with Pin1 binding site pS72 手法: X-RAY DIFFRACTION / 解像度: 1.5 Å PDB-7axn: 14-3-3 sigma in complex with Pin1 binding site pS72 and covalently bound TCF521-026 手法: X-RAY DIFFRACTION / 解像度: 1.4 Å PDB-7ayf: 14-3-3 sigma with Pin1 binding site pS72 and covalently bound TCF521-110 手法: X-RAY DIFFRACTION / 解像度: 1.752 Å PDB-7az1: 14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1013 手法: X-RAY DIFFRACTION / 解像度: 1.15 Å PDB-7az2: 14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1014 手法: X-RAY DIFFRACTION / 解像度: 1.081 Å PDB-7bdp: 14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1017 手法: X-RAY DIFFRACTION / 解像度: 1.75 Å PDB-7bdt: 14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1009 手法: X-RAY DIFFRACTION / 解像度: 1.75 Å PDB-7bdy: 14-3-3 sigma with Pin1 binding site pS72 and covalently bound PC2068B 手法: X-RAY DIFFRACTION / 解像度: 1.801 Å PDB-7bfw: 14-3-3 sigma with Pin1 binding site pS72 and covalently bound PC2068A 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-7bg3: 14-3-3 sigma with Pin1 binding site pS72 and covalently bound PC2046 手法: X-RAY DIFFRACTION / 解像度: 1.4 Å PDB-7bgq: 14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1019 手法: X-RAY DIFFRACTION / 解像度: 1.75 Å PDB-7bgr: 14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1016 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-7bgv: 14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1012 手法: X-RAY DIFFRACTION / 解像度: 1.683 Å PDB-7bgw: 14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1011 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-7nif: 14-3-3 sigma with Pin1 binding site pS72 and covalently bound TCF521-011 手法: X-RAY DIFFRACTION / 解像度: 1.71 Å PDB-7nig: 14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1008 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-7nix: 14-3-3 sigma with AS160 binding site pT642 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-7nj6: 14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1005 手法: X-RAY DIFFRACTION / 解像度: 1.59 Å PDB-7nj8: 14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1007 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-7nja: 14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1006 手法: X-RAY DIFFRACTION / 解像度: 1.75 Å PDB-7nqp: 14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound LvD1009 手法: X-RAY DIFFRACTION / 解像度: 1.24 Å PDB-7nrk: 14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1002F1 手法: X-RAY DIFFRACTION / 解像度: 1.75 Å PDB-7nrl: 14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1032 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-7nsv: 14-3-3 sigma with p65 (RelA) binding site pS45 and covalently bound PC2046 手法: X-RAY DIFFRACTION / 解像度: 1.33 Å
化合物	ChemComp-CA: Unknown entry / カルシウムジカチオン ChemComp-CL: Unknown entry / クロリド ChemComp-HOH: WATER ChemComp-S6B: 3-chloranyl-4-imidazol-1-yl-benzaldehyde ChemComp-S9E: 6-(2-bromanylimidazol-1-yl)pyridine-3-carbaldehyde ChemComp-SGH: 1-[4-methyl-3-(trifluoromethyl)phenyl]-2-phenyl-imidazole ChemComp-SFW: 1-[4-methyl-2-(trifluoromethyl)phenyl]-2-phenyl-imidazole ChemComp-TJB: 2-chloranyl-4-(2-phenylimidazol-1-yl)benzaldehyde ChemComp-MG: Unknown entry / マグネシウムジカチオン ChemComp-TJ8: 2-bromanyl-4-(2-phenylimidazol-1-yl)benzaldehyde ChemComp-TJK: 2-bromanyl-4-[2-(5-bromanyl-2-fluoranyl-phenyl)imidazol-1-yl]benzaldehyde ChemComp-TKH: [4-[2-[2,4-bis(fluoranyl)phenyl]imidazol-1-yl]-2-bromanyl-phenyl]methanol ChemComp-TKK: 1-(3-bromanyl-4-methyl-phenyl)-2-(2-bromophenyl)imidazole ChemComp-TL8: 2-methoxy-4-(2-phenylimidazol-1-yl)benzaldehyde ChemComp-TQK: 2-methyl-4-(2-phenylimidazol-1-yl)benzaldehyde ChemComp-TLK: 3-methoxy-4-(2-phenylimidazol-1-yl)benzaldehyde ChemComp-TLQ: 4-(2-phenylimidazol-1-yl)naphthalene-1-carbaldehyde ChemComp-NA: Unknown entry / ナトリウムカチオン ChemComp-P5N: 1-(4-methylphenyl)imidazole / 4-(1H-イミダゾ-ル-1-イル)ベンズアルデヒド ChemComp-UFH: 2-bromanyl-4-imidazol-1-yl-benzaldehyde ChemComp-NHE: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID / 2-(シクロヘキシルアミノ)エタンスルホン酸 / pH緩衝剤YM ChemComp-UG5: 4-[4-(trifluoromethyl)imidazol-1-yl]benzaldehyde ChemComp-JFS: [4-(1H-benzimidazol-1-yl)phenyl]methanol ChemComp-UG2: [4-(2-phenylimidazol-1-yl)phenyl]methanol ChemComp-UPQ: 4-(4-methylimidazol-1-yl)benzaldehyde ChemComp-PEG: DI(HYDROXYETHYL)ETHER / ジエチレングリコ-ル ChemComp-UPK: 2-(hydroxymethyl)-5-(2-phenylimidazol-1-yl)phenol ChemComp-GOL: GLYCEROL / グリセロ-ル ChemComp-UQN*: 1-(3-bromanyl-4-methyl-phenyl)-2-(2-bromophenyl)imidazole
由来	homo sapiens (ヒト)
キーワード	PEPTIDE BINDING PROTEIN / 1433 / Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 / TBC1 domain family member 4 / peptide-protein complex / benzaldehyde / covalent fragment / p65 / imine formation