タイトル | Crystal Structure of a Mycoestrogen-Detoxifying Lactonase from Rhinocladiella mackenziei: Molecular Insight into ZHD Substrate Selectivity |
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ジャーナル・号・ページ | Acs Catalysis, Vol. 8, Page 4294-4298, Year 2018 |
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掲載日 | 2017年5月27日 (構造データの登録日) |
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著者 | Zheng, Y.Y. / Liu, W.T. / Chen, C.C. / Hu, X.Y. / Liu, W.D. / Ko, T.P. / Tang, X.K. / Wei, H.L. / Huang, J.W. / Guo, R.T. |
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リンク | Acs Catalysis / PubMedで検索 |
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手法 | X線回折 |
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解像度 | 1.88 - 2.38 Å |
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構造データ | PDB-5xo6: Crystal structure of a novel ZEN lactonase mutant 手法: X-RAY DIFFRACTION / 解像度: 2.38 Å PDB-5xo7: Crystal structure of a novel ZEN lactonase mutant with ligand a 手法: X-RAY DIFFRACTION / 解像度: 1.88 Å PDB-5xo8: Crystal structure of a novel ZEN lactonase mutant with ligand Z 手法: X-RAY DIFFRACTION / 解像度: 1.88 Å PDB-5z5j: Crystal structure of a lactonase double mutant 手法: X-RAY DIFFRACTION / 解像度: 2.15 Å PDB-5z7j: Crystal structure of a lactonase double mutant in complex with ligand l 手法: X-RAY DIFFRACTION / 解像度: 1.98 Å PDB-5z97: Crystal structure of a lactonase double mutant in complex with ligand N 手法: X-RAY DIFFRACTION / 解像度: 2.32 Å |
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化合物 | ChemComp-36J: (3S,7R,11E)-7,14,16-trihydroxy-3-methyl-3,4,5,6,7,8,9,10-octahydro-1H-2-benzoxacyclotetradecin-1-one / 2β-メチル-6α,15,17-トリヒドロキシ-12,13-ブタノ-1-オキサシクロテトラデカン-10,15(13),(以下略)
ChemComp-ZER: (3S,11E)-14,16-dihydroxy-3-methyl-3,4,5,6,9,10-hexahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione / ゼアラレノン / toxin*YM
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由来 | - rhinocladiella mackenziei cbs 650.93 (菌類)
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キーワード | HYDROLASE / ALPHA/BETA-HYDROLASE / LACTONASE / ZEARALENONE |
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