EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Structural Basis for the Species-Selective Binding of N,C-Capped Dipeptides to the Mycobacterium tuberculosis Proteasome.
ジャーナル・号・ページ	Biochemistry, Vol. 56, Page 324-333, Year 2017
掲載日	2016年9月30日 (構造データの登録日)
著者	Hsu, H.C. / Singh, P.K. / Fan, H. / Wang, R. / Sukenick, G. / Nathan, C. / Lin, G. / Li, H.
リンク	Biochemistry / PubMed:27976853
手法	X線回折
解像度	2.804 - 3.103 Å
構造データ	PDB-5tho: Crystal Structure of Mycobacterium Tuberculosis Proteasome in complex with N,C-capped Dipeptide Inhibitor PKS2205 手法: X-RAY DIFFRACTION / 解像度: 3.002 Å PDB-5trg: Structure of Mycobacterium tuberculosis proteasome in complex with N,C-capped dipeptide DPLG-2 手法: X-RAY DIFFRACTION / 解像度: 2.804 Å PDB-5trr: Structure of Mycobacterium tuberculosis proteasome in complex with N,C-capped dipeptide PKS2169 手法: X-RAY DIFFRACTION / 解像度: 3.103 Å PDB-5trs: Structure of Mycobacterium tuberculosis proteasome in complex with N,C-capped dipeptide PKS2144 手法: X-RAY DIFFRACTION / 解像度: 3.08356699278 Å PDB-5try: Structure of Mycobacterium tuberculosis proteasome in complex with N,C-capped dipeptide PKS2206 手法: X-RAY DIFFRACTION / 解像度: 3.00000818194 Å PDB-5ts0: Structure of Mycobacterium tuberculosis proteasome in complex with N,C-capped dipeptide PKS2208 手法: X-RAY DIFFRACTION / 解像度: 2.84679745871 Å
化合物	ChemComp-7C7: N,N-diethyl-N~2~-(3-phenylpropanoyl)-L-asparaginyl-O-methyl-N-[(naphthalen-1-yl)methyl]-L-serinamide ChemComp-HOH: WATER / 水 ChemComp-7HJ: N,N-diethyl-N~2~-[(2E)-3-phenylprop-2-enoyl]-L-asparaginyl-4-fluoro-N-[(naphthalen-1-yl)methyl]-L-phenylalaninamide ChemComp-7HY: N,N-diethyl-N~2~-(3-phenylpropanoyl)-L-asparaginyl-N-[(naphthalen-1-yl)methyl]-L-alaninamide ChemComp-7HZ: N-tert-butoxy-N~2~-(5-methyl-1,2-oxazole-3-carbonyl)-L-asparaginyl-O-methyl-N-[(naphthalen-1-yl)methyl]-L-serinamide ChemComp-7J0: (2~{S})-~{N}-[(2~{S})-3-methoxy-1-(naphthalen-1-ylmethylamino)-1-oxidanylidene-propan-2-yl]-4-oxidanylidene-2-(3-phenylpropanoylamino)-4-piperidin-1-yl-butanamide ChemComp-7J1: (2S)-N-{(2S)-3-methoxy-1-[(naphthalen-1-ylmethyl)amino]-1-oxopropan-2-yl}-4-oxo-2-[(3-phenylpropanoyl)amino]-4-(1H-pyrrol-1-yl)butanamide (non-preferred name)
由来	mycobacterium tuberculosis (strain atcc 25177 / h37ra) (結核菌) mycobacterium tuberculosis (結核菌)
キーワード	hydrolase/hydrolase inhibitor / Dipeptide Inhibitor / proteasome (プロテアソーム) / Mycobacterium Tuberculosis (結核菌) / hydrolase-hydrolase inhibitor complex / N / C-capped dipeptides / DPLG-2 / proteasome inhibitors / C-capped dipeptide / inhibitors / HYDRONLASE/HYDROLASE inhibitor / HYDRONLASE-HYDROLASE inhibitor complex