タイトル | alpha-Helix or beta-Turn? An Investigation into N-Terminally Constrained Analogues of Glucagon-like Peptide 1 (GLP-1) and Exendin-4. |
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ジャーナル・号・ページ | Biochemistry, Vol. 57, Page 4148-4154, Year 2018 |
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掲載日 | 2017年8月22日 (構造データの登録日) |
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著者 | Oddo, A. / Mortensen, S. / Thogersen, H. / De Maria, L. / Hennen, S. / McGuire, J.N. / Kofoed, J. / Linderoth, L. / Reedtz-Runge, S. |
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リンク | Biochemistry / PubMed:29877701 |
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手法 | X線回折 |
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解像度 | 1.8 - 2.1 Å |
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構造データ | PDB-5ott: Extracellular domain of GLP-1 receptor in complex with exendin-4 variant Gly2Hcs/Thr5Hcs 手法: X-RAY DIFFRACTION / 解像度: 1.92 Å PDB-5otu: Extracellular domain of GLP-1 receptor in complex with GLP-1 variant Ala8Hcs/Thr11Hcs 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-5otv: Extracellular domain of GLP-1 receptor in complex with GLP-1 variant Ala8Cyc/Thr11Hcs 手法: X-RAY DIFFRACTION / 解像度: 2 Å PDB-5otw: Extracellular domain of GLP-1 receptor in complex with GLP-1 variant Ala8Hcs/Thr11Cys 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å PDB-5otx: Extracellular domain of GLP-1 receptor in complex with GLP-1 variant Ala8Cys/Thr11Cys 手法: X-RAY DIFFRACTION / 解像度: 2 Å |
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化合物 | |
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由来 | homo sapiens (ヒト) heloderma suspectum (爬虫類)
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キーワード | SIGNALING PROTEIN / glucagon-like peptide 1 / GPCR / cyclic peptides |
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