EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Structure and function of L-threonine-3-dehydrogenase from the parasitic protozoan Trypanosoma brucei revealed by X-ray crystallography and geometric simulations.
ジャーナル・号・ページ	Acta Crystallogr D Struct Biol, Vol. 74, Page 861-876, Year 2018
掲載日	2016年5月21日 (構造データの登録日)
著者	Adjogatse, E. / Erskine, P. / Wells, S.A. / Kelly, J.M. / Wilden, J.D. / Chan, A.W.E. / Selwood, D. / Coker, A. / Wood, S. / Cooper, J.B.
リンク	Acta Crystallogr D Struct Biol / PubMed:30198897
手法	X線回折
解像度	1.45 - 2.3 Å
構造データ	PDB-5k4q: Three-dimensional structure of L-threonine 3-dehydrogenase from Trypanosoma brucei bound to NAD+ refined to 2.3 angstroms 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å PDB-5k4t: Three-dimensional structure of L-threonine 3-dehydrogenase from Trypanosoma brucei refined to 2.1 angstroms 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å PDB-5k4u: Three-dimensional structure of L-threonine 3-dehydrogenase from Trypanosoma brucei showing different active site loop conformations between dimer subunits, refined to 1.9 angstroms 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-5k4v: Three-dimensional structure of L-threonine 3-dehydrogenase from Trypanosoma brucei bound to NAD+ refined to 2.2 angstroms 手法: X-RAY DIFFRACTION / 解像度: 2.2 Å PDB-5k4w: Three-dimensional structure of L-threonine 3-dehydrogenase from Trypanosoma brucei bound to NADH and L-threonine refined to 1.72 angstroms 手法: X-RAY DIFFRACTION / 解像度: 1.72 Å PDB-5k4y: Three-dimensional structure of L-threonine 3-dehydrogenase from Trypanosoma brucei refined to 1.77 angstroms 手法: X-RAY DIFFRACTION / 解像度: 1.77 Å PDB-5k50: Three-dimensional structure of L-threonine 3-dehydrogenase from Trypanosoma brucei bound to NAD+ and L-allo-threonine refined to 2.23 angstroms 手法: X-RAY DIFFRACTION / 解像度: 2.26 Å PDB-5l9a: L-threonine dehydrogenase from trypanosoma brucei. 手法: X-RAY DIFFRACTION / 解像度: 1.45 Å PDB-5lc1: L-threonine dehydrogenase from Trypanosoma brucei with NAD and the inhibitor pyruvate bound. 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å
化合物	ChemComp-NAD: NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NADYM ChemComp-GOL: GLYCEROL / グリセロ-ル ChemComp-SO4: SULFATE ION / 硫酸ジアニオン ChemComp-HOH: WATER ChemComp-ACT: ACETATE ION / 酢酸イオン ChemComp-NA: Unknown entry / ナトリウムカチオン ChemComp-NAI: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE / NADH ChemComp-THR: THREONINE / トレオニン ChemComp-CL: Unknown entry / クロリド ChemComp-ALO: ALLO-THREONINE / L-アロトレオニン ChemComp-PYR: PYRUVIC ACID / ピルビン酸 ChemComp-BME*: BETA-MERCAPTOETHANOL / 2-メルカプトエタノ-ル
由来	trypanosoma brucei (トリパノソーマ)
キーワード	OXIDOREDUCTASE / short-chain dehydrogenase / ligand-bound / holo / apo / oxidoreuctase / threonine / Apo-enzyme / Rossmann fold / dehydrogenase / holo-enzyme / Rossman fold