EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Structural Analysis of Glycine Sarcosine N-methyltransferase from Methanohalophilus portucalensis Reveals Mechanistic Insights into the Regulation of Methyltransferase Activity.
ジャーナル・号・ページ	Sci Rep, Vol. 6, Page 38071-38071, Year 2016
掲載日	2016年9月14日 (構造データの登録日)
著者	Lee, Y.R. / Lin, T.S. / Lai, S.J. / Liu, M.S. / Lai, M.C. / Chan, N.L.
リンク	Sci Rep / PubMed:27934872
手法	X線回折
解像度	1.776 - 2.471 Å
構造データ	PDB-5gwx: Crystal structure of glycine sarcosine N-methyltransferase from Methanohalophilus portucalensis in complex with S-adenosylmethionine and sarcosine 手法: X-RAY DIFFRACTION / 解像度: 2.205 Å PDB-5h02: Crystal structure of Methanohalophilus portucalensis glycine sarcosine N-methyltransferase tetramutant (H21G, E23T, E24N, L28S) 手法: X-RAY DIFFRACTION / 解像度: 1.776 Å PDB-5hii: Crystal structure of glycine sarcosine N-methyltransferase (GSMT) from Methanohalophilus portucalensis (apo form) 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-5hij: Crystal structure of glycine sarcosine N-methyltransferase from Methanohalophilus portucalensis in complex with betaine 手法: X-RAY DIFFRACTION / 解像度: 1.93 Å PDB-5hik: Crystal structure of glycine sarcosine N-methyltransferase from Methanohalophilus portucalensis in complex with S-adenosylmethionine 手法: X-RAY DIFFRACTION / 解像度: 2.354 Å PDB-5hil: Crystal structure of glycine sarcosine N-methyltransferase from Methanohalophilus portucalensis in complex with S-adenosylhomocysteine and sarcosine 手法: X-RAY DIFFRACTION / 解像度: 2.471 Å PDB-5him: Crystal structure of glycine sarcosine N-methyltransferase from Methanohalophilus portucalensis in complex with S-adenosylhomocysteine and dimethylglycine 手法: X-RAY DIFFRACTION / 解像度: 2.338 Å
化合物	ChemComp-SAM: S-ADENOSYLMETHIONINE ChemComp-SAR: SARCOSINE / サルコシン ChemComp-EDO: 1,2-ETHANEDIOL / エチレングリコ-ル ChemComp-HOH: WATER ChemComp-SAH: S-ADENOSYL-L-HOMOCYSTEINE / S-アデノシルホモシステイン ChemComp-BET: TRIMETHYL GLYCINE / ベタイニウム ChemComp-DMG: N,N-DIMETHYLGLYCINE / N,N-ジメチルグリシン
由来	methanohalophilus portucalensis fdf-1 (古細菌)
キーワード	TRANSFERASE / S-adenosylmethionine-dependent methyltransferases / SAM / AdoMet-MTase / class I monomethylation / glycine / sarcosine rate-limiting enzyme / betaine biosynthesis betaine-mediated feedback inhibition / sarcosine / rate-limiting enzyme / betaine biosynthesis / betaine-mediated feedback inhibition / S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase) / class I / monomethylation of glycine and sarcosine / rate-limiting enzyme in betaine biosynthesis