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-Structure paper
Title | Structural Analysis of Glycine Sarcosine N-methyltransferase from Methanohalophilus portucalensis Reveals Mechanistic Insights into the Regulation of Methyltransferase Activity. |
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Journal, issue, pages | Sci Rep, Vol. 6, Page 38071-38071, Year 2016 |
Publish date | Sep 14, 2016 (structure data deposition date) |
Authors | Lee, Y.R. / Lin, T.S. / Lai, S.J. / Liu, M.S. / Lai, M.C. / Chan, N.L. |
External links | Sci Rep / PubMed:27934872 |
Methods | X-ray diffraction |
Resolution | 1.776 - 2.471 Å |
Structure data | PDB-5gwx: PDB-5h02: PDB-5hii: PDB-5hij: PDB-5hik: PDB-5hil: PDB-5him: |
Chemicals | ChemComp-SAM: ChemComp-SAR: ChemComp-EDO: ChemComp-HOH: ChemComp-SAH: ChemComp-BET: ChemComp-DMG: |
Source |
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Keywords | TRANSFERASE / S-adenosylmethionine-dependent methyltransferases / SAM / AdoMet-MTase / class I monomethylation / glycine / sarcosine rate-limiting enzyme / betaine biosynthesis betaine-mediated feedback inhibition / sarcosine / rate-limiting enzyme / betaine biosynthesis / betaine-mediated feedback inhibition / S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase) / class I / monomethylation of glycine and sarcosine / rate-limiting enzyme in betaine biosynthesis |