EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Mycobacterium tuberculosis IMPDH in Complexes with Substrates, Products and Antitubercular Compounds.
ジャーナル・号・ページ	Plos One, Vol. 10, Page e0138976-e0138976, Year 2015
掲載日	2015年5月10日 (構造データの登録日)
著者	Makowska-Grzyska, M. / Kim, Y. / Gorla, S.K. / Wei, Y. / Mandapati, K. / Zhang, M. / Maltseva, N. / Modi, G. / Boshoff, H.I. / Gu, M. ...Makowska-Grzyska, M. / Kim, Y. / Gorla, S.K. / Wei, Y. / Mandapati, K. / Zhang, M. / Maltseva, N. / Modi, G. / Boshoff, H.I. / Gu, M. / Aldrich, C. / Cuny, G.D. / Hedstrom, L. / Joachimiak, A.
リンク	Plos One / PubMed:26440283
手法	X線回折
解像度	1.602 - 2 Å
構造データ	PDB-4zqm: Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis in the complex with XMP and NAD 手法: X-RAY DIFFRACTION / 解像度: 1.602 Å PDB-4zqn: Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis in the complex with IMP and the inhibitor P41 手法: X-RAY DIFFRACTION / 解像度: 2 Å PDB-4zqo: Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis in the complex with IMP and the inhibitor Q67 手法: X-RAY DIFFRACTION / 解像度: 1.76 Å PDB-4zqp: Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis in the complex with IMP and the inhibitor MAD1 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-4zqr: Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis 手法: X-RAY DIFFRACTION / 解像度: 1.692 Å
化合物	ChemComp-XMP: XANTHOSINE-5'-MONOPHOSPHATE ChemComp-NAD: NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NADYM ChemComp-HOH: WATER ChemComp-IMP: INOSINIC ACID / IMP ChemComp-4QO: 2-chloro-N,N-dimethyl-5-[({2-[3-(prop-1-en-2-yl)phenyl]propan-2-yl}carbamoyl)amino]benzamide ChemComp-Q67: N~2~-(2,3-dichlorophenyl)-N-[2-(pyridin-4-yl)-1,3-benzoxazol-5-yl]-L-alaninamide / N-[2-(4-ピリジニル)ベンゾオキサゾ-ル-5-イル]-N²-(2,3-ジクロロフェニル)-(以下略) ChemComp-K: Unknown entry / カリウムカチオン ChemComp-GOL: GLYCEROL / グリセロ-ル ChemComp-PGO: S-1,2-PROPANEDIOL / (S)-1,2-プロパンジオ-ル ChemComp-KP3: 5'-O-({1-[(2E)-4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-2-methylbut-2-en-1-yl]-1H-1,2,3-triazol-4-yl}methyl)adenosine ChemComp-PO4*: PHOSPHATE ION / ホスファ-ト
由来	mycobacterium tuberculosis (strain atcc 25618 / h37rv) (結核菌)
キーワード	OXIDOREDUCTASE / IMPDH / delta-CBS / Mycobacterium tuberculosis / Structural Genomics / Center for Structural Genomics of Infectious Diseases / CSGID / Oxidoreductase/Oxidoreductase inhibitor / delta CBS / Oxidoreductase-Oxidoreductase inhibitor complex / MAD1 / Center for Membrane Proteins of Infectious Diseases